Steroids: From Physiology to Clinical Medicine

InTech, 2012. — 220 p. ISBN 9535108573; 9789535108573.This book covers contemporary basic science on steroids research, along with steroids practical application in clinical medicine. In response to the need to address novel and valuable information on steroids science and medicine, this book will enable readers to comprehend this fast-growing and exciting scientific discipline. The book starts by describing physiological and pathophysiological roles of steroids, with reference to production and action of gonadal steroids, role of steroid sulfonation, sex specific and steroids-dependent mechanism of hippocampal function, and the hydroxysteroid dehydrogenases for the modulation of tissue glucocorticoid availability. Then authors covered different aspects of steroids application in clinical environment, such as endocrine function after ovarian transplantation, diagnostic significance of salivary assessment of androgens, drawbacks of steroids use in sport, analysis of serum steroid hormone profiles in patients with adrenocortical tumors, and correlation between salivary and serum cortisol responses after alcohol intake.Contents:
Physiology and Pathophysiology of Steroids.
Gonadal Sex Steroids: Production, Action and Interactions in Mammals.
The Biological Roles of Steroid Sulfbnation.
Hippocampal Function and Gonadal Steroids.
llp-Hydroxysteroid Dehydrogenases in the Regulation of Tissue Glucocorticoid Availability.
Steroids: Clinical Application.
Sex Steroid Production from Cryopreserved and Re implanted Ovarian Tissue.
Female Salivary Testosterone: Measurement, Challenges and Applications.
Limits of Anabolic Steroids Application in Sport and Exercise.
Steroidogenic Enzyme 17,20-Lyase Activity in Cortisolsecreting and Non-functioning Adrenocortica.
Salivary or Serum Cortisol: Possible Implications for Alcohol Research.